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Norrie Disease (Pseudoglioma) 抗体 (AA 25-133) (HRP)

NDP 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7161712
发货至: 中国
  • 抗原 See all Norrie Disease (Pseudoglioma) (NDP) 抗体
    Norrie Disease (Pseudoglioma) (NDP)
    抗原表位
    • 12
    • 3
    • 2
    • 1
    • 1
    AA 25-133
    适用
    • 34
    • 13
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 32
    • 3
    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This Norrie Disease (Pseudoglioma) antibody is conjugated to HRP
    应用范围
    • 12
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Norrin protein (25-133AA)
    亚型
    IgG
    Top Product
    Discover our top product NDP Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Norrie Disease (Pseudoglioma) (NDP)
    别名
    NDP (NDP 产品)
    背景

    Background: Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.

    Aliases: EVR2 antibody, Exudative vitreoretinopathy 2 (X linked) antibody, FEVR antibody, ND antibody, NDP antibody, NDP_HUMAN antibody, Norrie disease (pseudoglioma) antibody, Norrie disease protein antibody, Norrin antibody, Norrin precursor antibody, X linked exudative vitreoretinopathy 2 protein antibody, X-linked exudative vitreoretinopathy 2 protein antibody

    UniProt
    Q00604
    途径
    Sensory Perception of Sound
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