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Norrie Disease (Pseudoglioma) 抗体 (AA 25-133) (FITC)

NDP 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7161711
发货至: 中国
  • 抗原 See all Norrie Disease (Pseudoglioma) (NDP) 抗体
    Norrie Disease (Pseudoglioma) (NDP)
    抗原表位
    • 12
    • 3
    • 2
    • 1
    • 1
    AA 25-133
    适用
    • 34
    • 13
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 32
    • 3
    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Norrie Disease (Pseudoglioma) antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Norrin protein (25-133AA)
    亚型
    IgG
    Top Product
    Discover our top product NDP Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Norrie Disease (Pseudoglioma) (NDP)
    别名
    NDP (NDP 产品)
    别名
    EVR2 antibody, FEVR antibody, ND antibody, evr2 antibody, fevr antibody, xnorrin antibody, Ndph antibody, RGD1563968 antibody, NDP, norrin cystine knot growth factor antibody, Norrie disease (pseudoglioma) L homeolog antibody, Norrie disease (pseudoglioma) (human) antibody, NDP antibody, ndp.L antibody, Ndp antibody
    背景

    Background: Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.

    Aliases: EVR2 antibody, Exudative vitreoretinopathy 2 (X linked) antibody, FEVR antibody, ND antibody, NDP antibody, NDP_HUMAN antibody, Norrie disease (pseudoglioma) antibody, Norrie disease protein antibody, Norrin antibody, Norrin precursor antibody, X linked exudative vitreoretinopathy 2 protein antibody, X-linked exudative vitreoretinopathy 2 protein antibody

    UniProt
    Q00604
    途径
    Sensory Perception of Sound
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