-
- 抗原 See all Lipocalin 2 (LCN2) 抗体
- Lipocalin 2 (LCN2)
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Lipocalin 2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Protein G purified
- 免疫原
- Recombinant Human Neutrophil gelatinase-associated lipocalin protein
- 克隆位点
- 1A1B2
- 亚型
- IgG2b
- Top Product
- Discover our top product LCN2 Primary Antibody
-
anti-Lipocalin 2 (LCN2) (AA 21-200) antibody
LCN2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-200) antibodyLCN2 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 101-198) antibodyLCN2 适用: 人 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 1-100) antibodyLCN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D14 unconjugated
anti-Lipocalin 2 (LCN2) (AA 1-198) antibodyLCN2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 1-198) antibodyLCN2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- Lipocalin 2 (LCN2)
- 别名
- LCN2 (LCN2 产品)
- 别名
- LCN2 antibody, 24p3 antibody, MSFI antibody, NGAL antibody, AW212229 antibody, Sip24 antibody, lipocalin 2 antibody, LCN2 antibody, Lcn2 antibody
- 背景
-
Background: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.
Aliases: 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3, p25, LCN2, HNL, NGAL
- UniProt
- P80188
- 途径
- Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
-
You are here:
