Neuropilin 1 抗体 (AA 684-923)
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- 抗原 See all Neuropilin 1 (NRP1) 抗体
- Neuropilin 1 (NRP1)
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抗原表位
- AA 684-923
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neuropilin 1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity purified
- 免疫原
- Recombinant Human Neuropilin-1 protein (684-923AA)
- 亚型
- IgG
- Top Product
- Discover our top product NRP1 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Neuropilin 1 (NRP1)
- 别名
- NRP1 (NRP1 产品)
- 别名
- NRP1 antibody, cd304 antibody, neuropilin antibody, np-1 antibody, npn-1 antibody, nrp antibody, nrp-1 antibody, vegf165r antibody, BDCA4 antibody, CD304 antibody, NP1 antibody, NRP antibody, VEGF165R antibody, C530029I03 antibody, NP-1 antibody, NPN-1 antibody, Npn1 antibody, Nrp antibody, neuropilin 1 antibody, neuropilin 1 L homeolog antibody, NRP1 antibody, nrp1 antibody, Nrp1 antibody, nrp1.L antibody
- 背景
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Background: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
Aliases: A5 protein antibody, BDCA4 antibody, BLOOD DENDRITIC CELL ANTIGEN 4 antibody, CD304 antibody, Neuropilin-1 antibody, Neuropilin1 antibody, NP1 antibody, NPN1 antibody, NRP 1 antibody, NRP antibody, NRP1 antibody, NRP1_HUMAN antibody, transmembrane receptor antibody, Vascular endothelial cell growth factor 165 receptor antibody, VEGF165R antibody
- UniProt
- O14786
- 途径
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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