Neurexin 1 抗体 (AA 31-310)
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- 抗原 See all Neurexin 1 (NRXN1) 抗体
- Neurexin 1 (NRXN1)
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抗原表位
- AA 31-310
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neurexin 1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Neurexin-1 protein (31-310AA)
- 亚型
- IgG
- Top Product
- Discover our top product NRXN1 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Neurexin 1 (NRXN1)
- 别名
- NRXN1 (NRXN1 产品)
- 别名
- Hs.22998 antibody, PTHSL2 antibody, SCZD17 antibody, CG7050 antibody, CT21808 antibody, Dmel\\CG7050 antibody, Nrx antibody, Nrx1 antibody, dnrx antibody, dnrx-1 antibody, nrx antibody, Nrxn1b antibody, NRXN1 antibody, Nrx-1 antibody, GB13455 antibody, GB18754 antibody, 1700062G21Rik antibody, 9330127H16Rik antibody, A230068P09Rik antibody, mKIAA0578 antibody, neurexin 1 antibody, Neurexin 1 antibody, neurexin I antibody, neurexin 1b antibody, neurexin 1a antibody, NRXN1 antibody, Nrx-1 antibody, Nrxn1 antibody, nrxn1 antibody, nrxn1b antibody, nrxn1a antibody
- 背景
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Background: Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity).
Aliases: DKFZp313P2036 antibody, FLJ35941 antibody, Hs.22998 antibody, KIAA0578 antibody, Neurexin 1 alpha antibody, Neurexin 1 beta antibody, Neurexin I-alpha antibody, Neurexin-1 antibody, Neurexin-1-alpha antibody, NRX1A_HUMAN antibody, NRXN1 antibody, PTHSL2 antibody, SCZD17 antibody
- UniProt
- Q9ULB1
- 途径
- Synaptic Membrane, Skeletal Muscle Fiber Development
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