UNC5B 抗体 (AA 404-517) (HRP)
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- 抗原 See all UNC5B 抗体
- UNC5B (Netrin receptor UNC5B (UNC5B))
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抗原表位
- AA 404-517
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UNC5B antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Netrin receptor UNC5B protein (404-517AA)
- 亚型
- IgG
- Top Product
- Discover our top product UNC5B Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- UNC5B (Netrin receptor UNC5B (UNC5B))
- 别名
- UNC5B (UNC5B 产品)
- 别名
- unc5h2 antibody, 6330415E02Rik antibody, A630020F16 antibody, D10Bwg0792e antibody, Unc5h2 antibody, UNC5H2 antibody, p53RDL1 antibody, UNC5C antibody, UNC5B antibody, p53rdl1 antibody, unc-5 netrin receptor B antibody, unc-5 netrin receptor B L homeolog antibody, unc5b antibody, Unc5b antibody, UNC5B antibody, unc5b.L antibody
- 背景
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Background: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion (By similarity). Functions as netrin receptor that negatively regulates vascular branching during angiogenesis. Mediates retraction of tip cell filopodia on endothelial growth cones in response to netrin (By similarity). It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:12598906). Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity (By similarity).
Aliases: 6330415E02Rik antibody, A630020F16 antibody, D10Bwg0792e antibody, Netrin receptor UNC5B antibody, Netrin receptor UNC5B Precursor antibody, p53 regulated receptor for death and life antibody, p53 regulated receptor for death and life protein 1 antibody, p53-regulated receptor for death and life protein 1 antibody, p53RDL1 antibody, Protein unc-5 homolog 2 antibody, Protein unc-5 homolog B antibody, Protein XUNC 5 antibody, Transmembrane receptor Unc5H2 antibody, Unc 5 homolog 2 antibody, Unc 5 homolog B antibody, Unc 5 netrin receptor B antibody, UNC 5B antibody, Unc5 (C.elegans homolog) b antibody, Unc5b antibody, UNC5B_HUMAN antibody, UNC5H2 antibody
- UniProt
- Q8IZJ1
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