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- 抗原 See all SYNE2 抗体
- SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))
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抗原表位
- AA 1-176
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SYNE2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Nesprin-2 protein (1-176AA)
- 亚型
- IgG
- Top Product
- Discover our top product SYNE2 Primary Antibody
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anti-Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2) (AA 6-296) antibody
SYNE2 适用: 人 ELISA, WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2) (AA 6702-6799) antibodySYNE2 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 5E5 unconjugated
anti-Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2) (AA 1843-1877) antibodySYNE2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB56750 unconjugated
anti-Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2) (AA 6702-6799) antibodySYNE2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2) (AA 1-459) antibodySYNE2 适用: 人 WB, IP, ICC, IF, EM 宿主: 小鼠 Monoclonal K20-478-5 unconjugated
anti-Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2) antibodySYNE2 适用: 小鼠 WB, IP, ICC, IF 宿主: 兔 Monoclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))
- 别名
- SYNE2 (SYNE2 产品)
- 别名
- EDMD5 antibody, NUA antibody, NUANCE antibody, Nesp2 antibody, Nesprin-2 antibody, SYNE-2 antibody, TROPH antibody, SYNE2 antibody, nua antibody, edmd5 antibody, nuance antibody, syne-2 antibody, nesprin-2 antibody, 6820443O06Rik antibody, AW546258 antibody, D12Ertd777e antibody, Nesp2g antibody, mKIAA1011 antibody, RGD1305248 antibody, spectrin repeat containing nuclear envelope protein 2 antibody, spectrin repeat containing, nuclear envelope 2 antibody, SYNE2 antibody, syne2 antibody, Syne2 antibody
- 背景
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Background: Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. May be involved in nucleus-centrososme attachment. During interkinetic nuclear migration (INM) at G2 phase and nuclear migration in neural progenitors its LINC complex association with SUN1/2 and probable association with cytoplasmic dynein-dynactin motor complexes functions to pull the nucleus toward the centrosome, SYNE1 and SYNE2 may act redundantly. During INM at G1 phase mediates respective LINC complex association with kinesin to push the nucleus away from the centrosome. Involved in nuclear migration in retinal photoreceptor progenitors. Required for centrosome migration to the apical cell surface during early ciliogenesis.
Aliases: DKFZP434H2235 antibody, DKFZp686E01115 antibody, DKFZp686H1931 antibody, FLJ11014 antibody, FLJ43727 antibody, FLJ45710 antibody, FLJ46790 antibody, KIAA1011 antibody, Nesprin-2 antibody, Nesprin2 antibody, NUA antibody, NUANCE antibody, Nuclear envelope spectrin repeat protein 2 antibody, Nucleus and actin connecting element antibody, Nucleus and actin connecting element protein antibody, Protein NUANCE antibody, Spectrin repeat containing nuclear envelope 2 antibody, Synaptic nuclear envelope protein 2 antibody, Synaptic nuclei expressed gene 2 antibody, SYNE 2 antibody, Syne-2 antibody, SYNE2 antibody, SYNE2_HUMAN antibody
- UniProt
- Q8WXH0
- 途径
- Maintenance of Protein Location
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