WWP2 抗体 (AA 145-367)
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- 抗原 See all WWP2 抗体
- WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
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抗原表位
- AA 145-367
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WWP2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human NEDD4-like E3 ubiquitin-protein ligase WWP2 protein (145-367AA)
- 亚型
- IgG
- Top Product
- Discover our top product WWP2 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
- 别名
- WWP2 (WWP2 产品)
- 背景
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Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by \\\'Lys-63\\\'-linked conjugation and promotes it to proteasomal degradation, in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation, in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2, the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
Aliases: WWP2NEDD4-like E3 ubiquitin-protein ligase WWP2 antibody, EC 2.3.2.26 antibody, Atrophin-1-interacting protein 2 antibody, AIP2 antibody, HECT-type E3 ubiquitin transferase WWP2 antibody, WW domain-containing protein 2 antibody
- UniProt
- O00308
- 途径
- Negative Regulation of Transporter Activity
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