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MBNL1 抗体 (AA 1-382)

MBNL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7160357
发货至: 中国
  • 抗原 See all MBNL1 抗体
    MBNL1 (Muscleblind-like Protein 1 (MBNL1))
    抗原表位
    • 13
    • 10
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-382
    适用
    • 45
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 38
    • 6
    • 1
    克隆类型
    • 39
    • 6
    多克隆
    标记
    • 23
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBNL1 antibody is un-conjugated
    应用范围
    • 36
    • 24
    • 7
    • 7
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Muscleblind-like protein 1 protein (1-382AA)
    亚型
    IgG
    Top Product
    Discover our top product MBNL1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MBNL1 (Muscleblind-like Protein 1 (MBNL1))
    别名
    MBNL1 (MBNL1 产品)
    别名
    MBNL1 antibody, zgc:153954 antibody, Mbnl antibody, mKIAA0428 antibody, EXP antibody, EXP35 antibody, EXP40 antibody, EXP42 antibody, MBNL antibody, muscleblind like splicing regulator 1 antibody, muscleblind-like splicing regulator 1 antibody, muscleblind like splicing factor 1 antibody, MBNL1 antibody, mbnl1 antibody, Mbnl1 antibody
    背景

    Background: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5\'-YGCU(U/G)Y-3\'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.

    Aliases: EXP antibody, EXP35 antibody, EXP40 antibody, EXP42 antibody, KIAA0428 antibody, MBNL antibody, MBNL protein antibody, MBNL1 antibody, MBNL1_HUMAN antibody, Muscleblind 41kD isoform antibody, Muscleblind like antibody, Muscleblind like protein 1 antibody, Muscleblind like splicing regulator 1 antibody, Muscleblind-like protein 1 antibody, Triplet expansion RNA binding protein antibody, Triplet-expansion RNA-binding protein antibody

    UniProt
    Q9NR56
    途径
    Ribonucleoprotein Complex Subunit Organization
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