MBNL1 抗体 (AA 1-382)
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- 抗原 See all MBNL1 抗体
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
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抗原表位
- AA 1-382
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MBNL1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Muscleblind-like protein 1 protein (1-382AA)
- 亚型
- IgG
- Top Product
- Discover our top product MBNL1 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
- 别名
- MBNL1 (MBNL1 产品)
- 别名
- MBNL1 antibody, zgc:153954 antibody, Mbnl antibody, mKIAA0428 antibody, EXP antibody, EXP35 antibody, EXP40 antibody, EXP42 antibody, MBNL antibody, muscleblind like splicing regulator 1 antibody, muscleblind-like splicing regulator 1 antibody, muscleblind like splicing factor 1 antibody, MBNL1 antibody, mbnl1 antibody, Mbnl1 antibody
- 背景
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Background: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5\'-YGCU(U/G)Y-3\'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.
Aliases: EXP antibody, EXP35 antibody, EXP40 antibody, EXP42 antibody, KIAA0428 antibody, MBNL antibody, MBNL protein antibody, MBNL1 antibody, MBNL1_HUMAN antibody, Muscleblind 41kD isoform antibody, Muscleblind like antibody, Muscleblind like protein 1 antibody, Muscleblind like splicing regulator 1 antibody, Muscleblind-like protein 1 antibody, Triplet expansion RNA binding protein antibody, Triplet-expansion RNA-binding protein antibody
- UniProt
- Q9NR56
- 途径
- Ribonucleoprotein Complex Subunit Organization
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