MOBKL1A 抗体 (AA 2-216)
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- 抗原 See all MOBKL1A (MOB1B) 抗体
- MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
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抗原表位
- AA 2-216
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MOBKL1A antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human MOB kinase activator 1B protein (2-216AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:500-1:2000, IF:1:200-1:500, IP:1:200-1:2000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
- 别名
- MOB1B (MOB1B 产品)
- 别名
- MATS2 antibody, MOB4A antibody, MOBKL1A antibody, 1110003E08Rik antibody, AU015450 antibody, B230364F10 antibody, Mobkl1a antibody, mobkl1a antibody, mobkl1aa antibody, wu:fj65h03 antibody, zgc:56156 antibody, zgc:77872 antibody, MOB1B antibody, mob4a antibody, mats2 antibody, C2orf6 antibody, MOB1 antibody, MOBK1B antibody, Mob4B antibody, cb512 antibody, mobkl1ab antibody, sb:cb512 antibody, zgc:111840 antibody, MOB kinase activator 1B antibody, MOB kinase activator 1Ba antibody, Mps one binder kinase activator-like 1A antibody, mps one binder kinase activator-like 1A antibody, MOB kinase activator 1B L homeolog antibody, MOB kinase activator 1Bb antibody, MOB1B antibody, Mob1b antibody, mob1ba antibody, mol1a antibody, LOC100282811 antibody, LOC100285953 antibody, mob1b antibody, mob1b.L antibody, mob1bb antibody
- 背景
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Background: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.
Aliases: MATS 2 antibody, MATS2 antibody, MGC33910 antibody, Mob 1A antibody, Mob 1B antibody, MOB 4A antibody, MOB kinase activator 1B antibody, Mob1 homolog 1A antibody, MOB1 Mps One Binder homolog B antibody, MOB1 Mps one binder kinase activator like 1A antibody, Mob1A antibody, Mob1B antibody, MOBKL 1A antibody, MOBKL1A antibody, MOL1A_HUMAN antibody, Mps one binder kinase activator like 1A antibody, Mps one binder kinase activator-like 1A antibody, Protein Mob4A antibody
- UniProt
- Q7L9L4
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