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- 抗原 See all ASK1 (MAP3K5) 抗体
- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
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抗原表位
- AA 363-431
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASK1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Mitogen-activated protein kinase kinase kinase 5 protein (363-431AA)
- 亚型
- IgG
- Top Product
- Discover our top product MAP3K5 Primary Antibody
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (pThr845) antibody
MAP3K5 适用: 人, 小鼠, 大鼠, Cow WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) antibodyMAP3K5 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (AA 1231-1374) antibodyMAP3K5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (pSer966) antibodyMAP3K5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (AA 693-933) antibodyMAP3K5 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (AA 821-849) antibodyMAP3K5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12839 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (AA 1231-1374) antibodyMAP3K5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (N-Term) antibodyMAP3K5 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (pSer83) antibodyMAP3K5 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (C-Term) antibodyMAP3K5 适用: 人, 小鼠 WB, IHC, ELISA, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
- 别名
- MAP3K5 (MAP3K5 产品)
- 别名
- ASK1 antibody, MAPKKK5 antibody, MEKK5 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MUD21.11 antibody, MUD21_11 antibody, 7420452D20Rik antibody, ASK antibody, Mekk5 antibody, Ask1 antibody, RGD1306565 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MAP3K5 antibody, MAPKKK5 antibody, Map3k5 antibody, map3k5 antibody
- 背景
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Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens. Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF) or lipopolysaccharide (LPS). Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K4/SEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs). Both p38 MAPK and JNKs control the transcription factors activator protein-1 (AP-1).
Aliases: Apoptosis signal regulating kinase 1 antibody, Apoptosis signal-regulating kinase 1 antibody, ASK 1 antibody, ASK-1 antibody, ASK1 antibody, M3K5 antibody, M3K5_HUMAN antibody, MAP/ERK kinase kinase 5 antibody, MAP3K5 antibody, MAPK/ERK kinase kinase 5 antibody, MAPKKK5 antibody, MEK kinase 5 antibody, MEKK 5 antibody, MEKK5 antibody, Mitogen activated protein kinase kinase kinase 5 antibody, Mitogen-activated protein kinase kinase kinase 5 antibody
- UniProt
- Q99683
- 途径
- MAPK Pathway, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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