PIK3CD 抗体 (pTyr524) (Biotin)
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- 抗原 See all PIK3CD 抗体
- PIK3CD (Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD))
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抗原表位
- pTyr524
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIK3CD antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Dog,Cow,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human PIK3CD around the phosphorylation site of Tyr524
- 亚型
- IgG
- Top Product
- Discover our top product PIK3CD Primary Antibody
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anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (AA 774-1044) antibody
PIK3CD 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (AA 687-717), (C-Term) antibodyPIK3CD 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB1707 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (pTyr524) antibodyPIK3CD 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (AA 85-114), (N-Term) antibodyPIK3CD 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB11627 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (AA 51-150) antibodyPIK3CD 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (N-Term) antibodyPIK3CD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (AA 150-250) antibodyPIK3CD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (C-Term) antibodyPIK3CD 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (C-Term) antibodyPIK3CD 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD) (N-Term) antibodyPIK3CD 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- PIK3CD (Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide (PIK3CD))
- 别名
- PI 3 Kinase p110 delta (PIK3CD 产品)
- 别名
- 2410099E07Rik antibody, 2610208K16Rik antibody, AW545373 antibody, p110delta antibody, P110DELTA antibody, PI3K antibody, p110D antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta antibody, Pik3cd antibody, PIK3CD antibody
- 背景
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Synonyms: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PtdIns-3-kinase subunit delta, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, PtdIns-3-kinase subunit p110-delta, p110delta, PIK3CD
Background: Phosphoinositide-3-kinase (PI3K) that phosphorylates PftdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Mediates immune responses. Plays a role in B-cell development, proliferation, migration, and function. Required for B-cell receptor (BCR) signaling. Mediates B-cell proliferation response to anti-IgM, anti-CD40 and IL4 stimulation. Promotes cytokine production in response to TLR4 and TLR9. Required for antibody class switch mediated by TLR9. Involved in the antigen presentation function of B-cells. Involved in B-cell chemotaxis in response to CXCL13 and sphingosine 1-phosphate (S1P). Required for proliferation, signaling and cytokine production of naive, effector and memory T-cells. Required for T-cell receptor (TCR) signaling. Mediates TCR signaling events at the immune synapse. Activation by TCR leads to antigen-dependent memory T-cell migration and retention to antigenic tissues. Together with PIK3CG participates in T-cell development. Contributes to T-helper cell expansion and differentiation. Required for T-cell migration mediated by homing receptors SELL/CD62L, CCR7 and S1PR1 and antigen dependent recruitment of T-cells. Together with PIK3CG is involved in natural killer (NK) cell development and migration towards the sites of inflammation. Participates in NK cell receptor activation. Have a role in NK cell maturation and cytokine production. Together with PIK3CG is involved in neutrophil chemotaxis and extravasation. Together with PIK3CG participates in neutrophil respiratory burst. Have important roles in mast-cell development and mast cell mediated allergic response. Involved in stem cell factor (SCF)-mediated proliferation, adhesion and migration.
- 基因ID
- 5293
- UniProt
- O00329
- 途径
- BCR Signaling, Warburg Effect
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