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- 抗原 See all C20orf72 (MGME1) products
- C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
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抗原表位
- AA 81-260
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C20orf72 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Mitochondrial genome maintenance exonuclease 1 protein (81-260AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
- 别名
- MGME1 (MGME1 产品)
- 别名
- C20orf72 antibody, DDK1 antibody, MTDPS11 antibody, bA504H3.4 antibody, mitochondrial genome maintenance exonuclease 1 antibody, MGME1 antibody
- 背景
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Background: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5\'-3\' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
Aliases: MGME1 antibody, C20orf72 antibody, DDK1Mitochondrial genome maintenance exonuclease 1 antibody, EC 3.1.-.- antibody
- UniProt
- Q9BQP7
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