MACF1 抗体 (AA 1936-2150) (HRP)
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- 抗原 See all MACF1 抗体
- MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))
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抗原表位
- AA 1936-2150
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MACF1 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 protein (1936-2150AA)
- 亚型
- IgG
- Top Product
- Discover our top product MACF1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))
- 别名
- MACF1 (MACF1 产品)
- 别名
- ABP620 antibody, ACF7 antibody, MACF antibody, OFC4 antibody, Acf7 antibody, Aclp7 antibody, R74989 antibody, mKIAA0465 antibody, MACF1 antibody, fc46g01 antibody, wu:fc46g01 antibody, si:rp71-45k5.7 antibody, acf7 antibody, macf antibody, ofc4 antibody, abp620 antibody, DKFZp469K2016 antibody, Kiaa0754 antibody, mKIAA0754 antibody, microtubule-actin crosslinking factor 1 antibody, microtubule-actin crosslinking factor 1a antibody, microtubule-actin cross-linking factor 1 antibody, dual specificity protein kinase CLK3 antibody, microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 antibody, KIAA0754 antibody, RIKEN cDNA D830031N03 gene antibody, MACF1 antibody, Macf1 antibody, macf1a antibody, macf1 antibody, LOC100175356 antibody, LOC100514848 antibody, LOC100550622 antibody, KIAA0754 antibody, D830031N03Rik antibody
- 背景
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Background: Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells (By similarity).
Aliases: MACF1 antibody, ABP620 antibody, ACF7 antibody, KIAA0465 antibody, KIAA1251 antibody, Microtubule-actin cross-linking factor 1 antibody, isoforms 1/2/3/5 antibody, 620 kDa actin-binding protein antibody, ABP620 antibody, Actin cross-linking family protein 7 antibody, Macrophin-1 antibody, Trabeculin-alpha antibody
- UniProt
- Q9UPN3
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