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MBD1 抗体 (AA 106-355)

MBD1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7159609
发货至: 中国
  • 抗原 See all MBD1 抗体
    MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
    抗原表位
    • 15
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 106-355
    适用
    • 40
    • 19
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 31
    • 9
    克隆类型
    • 33
    • 7
    多克隆
    标记
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBD1 antibody is un-conjugated
    应用范围
    • 34
    • 13
    • 13
    • 11
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Methyl-CpG-binding domain protein 1 protein (106-355AA)
    亚型
    IgG
    Top Product
    Discover our top product MBD1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
    别名
    MBD1 (MBD1 产品)
    别名
    CXXC3 antibody, PCM1 antibody, RFT antibody, Cxxc3 antibody, CCDC11 antibody, methyl-CpG binding domain protein 1 antibody, MBD1 antibody, Mbd1 antibody
    背景

    Background: Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone methyltransferase SETDB1. Probably forms a complex with SETDB1 and ATF7IP that represses transcription and couples DNA methylation and histone \'Lys-9\' trimethylation. Isoform 1 and isoform 2 can also repress transcription from unmethylated promoters.

    Aliases: CXXC 3 antibody, CXXC-type zinc finger protein 3 antibody, CXXC3 antibody, MBD 1 antibody, Mbd1 antibody, MBD1_HUMAN antibody, MECP1 COMPLEX antibody, Methyl CpG binding domain protein 1 antibody, Methyl CpG binding domain protein 1 isoform PCM1 antibody, Methyl CpG binding protein MBD1 antibody, Methyl CpG binding protein splice variant 1 antibody, Methyl CpG binding protein splice variant 2 antibody, Methyl CpG binding protein splice variant 3 antibody, Methyl CpG binding protein splice variant 4 antibody, Methyl-CpG-binding domain protein 1 antibody, Methyl-CpG-binding protein MBD1 antibody, PCM 1 antibody, PCM1 antibody, Protein containing methyl-CpG-binding domain 1 antibody, Regulator of fibroblast growth factor 2 (FGF 2) transcription antibody, RFT antibody, The regulator of fibroblast growth factor 2(FGF 2) transcription antibody

    UniProt
    Q9UIS9
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