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METRNL 抗体 (AA 46-311)

METRNL 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7159569
发货至: 中国
  • 抗原 See all METRNL 抗体
    METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
    抗原表位
    • 12
    • 1
    • 1
    • 1
    • 1
    AA 46-311
    适用
    • 10
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 14
    • 2
    克隆类型
    • 16
    多克隆
    标记
    • 8
    • 4
    • 2
    • 2
    This METRNL antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Meteorin-like protein (46-311AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
    别名
    METRNL (METRNL 产品)
    别名
    9430048M07Rik antibody, BC019776 antibody, fc90a08 antibody, fj23b04 antibody, wu:fc90a08 antibody, wu:fj23b04 antibody, zgc:56225 antibody, meteorin like, glial cell differentiation regulator antibody, meteorin, glial cell differentiation regulator-like antibody, meteorin-like, glial cell differentiation regulator antibody, meteorin, glial cell differentiation regulator-like L homeolog antibody, METRNL antibody, Metrnl antibody, metrnl.L antibody, metrnl antibody
    背景

    Background: Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures.

    Aliases: Meteorin like glial cell differentiation regulator antibody, Meteorin, glial cell differentiation regulator like antibody, Meteorin-like protein antibody, METRL_HUMAN antibody, Metrnl antibody

    UniProt
    Q641Q3
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