KISS1 抗体 (AA 20-138)
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- 抗原 See all KISS1 抗体
- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
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抗原表位
- AA 20-138
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KISS1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Metastasis-suppressor KiSS-1 protein (20-138AA)
- 亚型
- IgG
- Top Product
- Discover our top product KISS1 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
- 别名
- KISS1 (KISS1 产品)
- 别名
- HH13 antibody, KiSS-1 antibody, metastatin antibody, Eseptin antibody, KiSS-1 metastasis-suppressor antibody, KISS1 antibody, kiss1 antibody, Kiss1 antibody
- 背景
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Background: Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.
Aliases: KISS 1 antibody, KiSS 1 metastasis suppressor antibody, Kiss1 antibody, KISS1_HUMAN antibody, Kisspeptin 1 antibody, Kisspeptin 10 antibody, Kisspeptin 13 antibody, Kisspeptin 14 antibody, Kisspeptin antibody, Kisspeptin-1 antibody, Kisspeptin-10 antibody, Kisspeptin-54 antibody, Kisspeptin1 antibody, Malignant melanoma metastasis suppressor antibody, Metastasis suppressor KiSS 1 antibody, Metastasis suppressor KiSS1 antibody, Metastin antibody, MGC39258 antibody
- UniProt
- Q15726
- 途径
- Positive Regulation of Peptide Hormone Secretion
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