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KISS1 抗体 (AA 20-138)

KISS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7159562
发货至: 中国
  • 抗原 See all KISS1 抗体
    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
    抗原表位
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-138
    适用
    • 32
    • 16
    • 4
    宿主
    • 32
    • 4
    克隆类型
    • 33
    • 3
    多克隆
    标记
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KISS1 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 9
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Metastasis-suppressor KiSS-1 protein (20-138AA)
    亚型
    IgG
    Top Product
    Discover our top product KISS1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
    别名
    KISS1 (KISS1 产品)
    别名
    HH13 antibody, KiSS-1 antibody, metastatin antibody, Eseptin antibody, KiSS-1 metastasis-suppressor antibody, KISS1 antibody, kiss1 antibody, Kiss1 antibody
    背景

    Background: Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.

    Aliases: KISS 1 antibody, KiSS 1 metastasis suppressor antibody, Kiss1 antibody, KISS1_HUMAN antibody, Kisspeptin 1 antibody, Kisspeptin 10 antibody, Kisspeptin 13 antibody, Kisspeptin 14 antibody, Kisspeptin antibody, Kisspeptin-1 antibody, Kisspeptin-10 antibody, Kisspeptin-54 antibody, Kisspeptin1 antibody, Malignant melanoma metastasis suppressor antibody, Metastasis suppressor KiSS 1 antibody, Metastasis suppressor KiSS1 antibody, Metastin antibody, MGC39258 antibody

    UniProt
    Q15726
    途径
    Positive Regulation of Peptide Hormone Secretion
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