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MBTPS1 抗体 (AA 187-400)

MBTPS1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7159372
发货至: 中国
  • 抗原 See all MBTPS1 抗体
    MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
    抗原表位
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 187-400
    适用
    • 28
    • 12
    • 11
    宿主
    • 27
    • 1
    克隆类型
    • 27
    • 1
    多克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBTPS1 antibody is un-conjugated
    应用范围
    • 14
    • 9
    • 8
    • 7
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Membrane-bound transcription factor site-1 protease protein (187-400aa)
    亚型
    IgG
    Top Product
    Discover our top product MBTPS1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:100-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
    别名
    MBTPS1 (MBTPS1 产品)
    别名
    PCSK8 antibody, S1P antibody, SKI-1 antibody, 0610038M03Rik antibody, AV003995 antibody, Ski1 antibody, mKIAA0091 antibody, S1p antibody, Ski-1 antibody, membrane bound transcription factor peptidase, site 1 antibody, membrane-bound transcription factor peptidase, site 1 antibody, MBTPS1 antibody, Mbtps1 antibody
    背景

    Background: Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.

    Aliases: Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin-isozyme 1) (SKI-1), MBTPS1, KIAA0091 S1P SKI1

    UniProt
    Q14703
    途径
    ER-Nucleus Signaling
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