CD46 抗体 (AA 164-325)
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- 抗原 See all CD46 抗体
- CD46
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抗原表位
- AA 164-325
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD46 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Membrane cofactor protein (164-325AA)
- 亚型
- IgG
- Top Product
- Discover our top product CD46 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CD46
- 别名
- CD46 (CD46 产品)
- 别名
- AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
- 背景
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Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
Aliases: AHUS2 antibody, Antigen defined by monoclonal antibody TRA 2 10 antibody, Antigen identified by monoclonal antibody TRA 2 10 antibody, CD46 antibody, CD46 antigen antibody, CD46 antigen complement regulatory protein antibody, CD46 Molecule antibody, CD46 Molecule complement regulatory protein antibody, Complement membrane cofactor protein antibody, MCP antibody, MCP_HUMAN antibody, Measles virus receptor antibody, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) antibody, Membrane cofactor protein antibody, MGC26544 antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Trophoblast leucocyte common antigen antibody, Trophoblast leukocyte common antigen antibody, Trophoblast lymphocyte cross reactive antigen antibody
- UniProt
- P15529
- 途径
- Regulation of Actin Filament Polymerization
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