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MAGEA2 抗体 (AA 1-104) (Biotin)

MAGEA2 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7159257
发货至: 中国
  • 抗原 See all MAGEA2 抗体
    MAGEA2 (Melanoma Antigen Family A, 2 (MAGEA2))
    抗原表位
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1-104
    适用
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 26
    • 2
    克隆类型
    • 26
    • 2
    多克隆
    标记
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAGEA2 antibody is conjugated to Biotin
    应用范围
    • 20
    • 18
    • 12
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Melanoma-associated antigen 2 protein (1-104AA)
    亚型
    IgG
    Top Product
    Discover our top product MAGEA2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MAGEA2 (Melanoma Antigen Family A, 2 (MAGEA2))
    别名
    MAGEA2 (MAGEA2 产品)
    别名
    Mage-a2 antibody, MAGEA2 antibody, CT1.2 antibody, MAGE2 antibody, MAGEA2A antibody, melanoma antigen, family A, 2 antibody, melanoma-associated antigen 2 antibody, MAGE family member A2 antibody, Magea2 antibody, LOC706218 antibody, MAGEA2 antibody
    背景

    Background: Reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites. Also represses p73/TP73 activity. Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination by TRIM28 potentially in presence of Ubl-conjugating enzyme UBE2H. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. Negatively regulates acetylation and sumoylation of PML and represses PML-induced p53/TP53 acetylation and activation.

    Aliases: MAGEA2 antibody, MAGE2 antibody, MAGEA2A, antibody, MAGEA2B antibody, MAGE2 antibody, MAGEA2 antibody, Melanoma-associated antigen 2 antibody, Cancer/testis antigen 1.2 antibody, CT1.2 antibody, MAGE-2 antigen antibody

    UniProt
    P43356
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