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RIKEN cDNA 4930404A10 Gene (4930404A10RIK) (AA 18-91) 抗体 (FITC)

4930404A10RIK 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7159185
发货至: 中国
  • 抗原 See all RIKEN cDNA 4930404A10 Gene (4930404A10RIK) 抗体
    RIKEN cDNA 4930404A10 Gene (4930404A10RIK)
    抗原表位
    AA 18-91
    适用
    宿主
    • 4
    克隆类型
    • 4
    多克隆
    标记
    • 1
    • 1
    • 1
    • 1
    FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Meiosis-specific kinetochore protein (18-91AA)
    亚型
    IgG
    Top Product
    Discover our top product 4930404A10RIK Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RIKEN cDNA 4930404A10 Gene (4930404A10RIK)
    别名
    MEIKIN (4930404A10RIK 产品)
    别名
    4930404A10Rik antibody, meiotic kinetochore factor antibody, Meikin antibody
    背景

    Background: Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis.

    Aliases: MEIKINMeiosis-specific kinetochore protein antibody

    UniProt
    A0A087WXM9
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