RIKEN cDNA 4930404A10 Gene (4930404A10RIK) (AA 18-91) 抗体
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- 抗原 See all RIKEN cDNA 4930404A10 Gene (4930404A10RIK) 抗体
- RIKEN cDNA 4930404A10 Gene (4930404A10RIK)
- 抗原表位
- AA 18-91
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
- 应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Meiosis-specific kinetochore protein (18-91AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RIKEN cDNA 4930404A10 Gene (4930404A10RIK)
- 别名
- MEIKIN (4930404A10RIK 产品)
- 别名
- 4930404A10Rik antibody, meiotic kinetochore factor antibody, Meikin antibody
- 背景
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Background: Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis.
Aliases: MEIKINMeiosis-specific kinetochore protein antibody
- UniProt
- A0A087WXM9
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