MED1 抗体 (AA 878-1031)
-
- 抗原 See all MED1 抗体
- MED1 (Mediator Complex Subunit 1 (MED1))
-
抗原表位
- AA 878-1031
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MED1 antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Mediator of RNA polymerase II transcription subunit 1 protein (878-1031AA)
- 亚型
- IgG
- Top Product
- Discover our top product MED1 Primary Antibody
-
-
- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- MED1 (Mediator Complex Subunit 1 (MED1))
- 别名
- MED1 (MED1 产品)
- 别名
- CRSP1 antibody, CRSP200 antibody, DRIP205 antibody, DRIP230 antibody, PBP antibody, PPARBP antibody, PPARGBP antibody, RB18A antibody, TRAP220 antibody, TRIP2 antibody, CRSP-1 antibody, MED1 antibody, pbp antibody, nbr1 antibody, crsp1 antibody, rb18a antibody, trip2 antibody, pparbp antibody, crsp200 antibody, drip205 antibody, drip230 antibody, ppargbp antibody, trap220 antibody, CG7162 antibody, Dmel\\CG7162 antibody, Med1 antibody, Med1/SOP3/TRAP220 antibody, Trap220 antibody, dTRAP220 antibody, AI480703 antibody, CRSP210 antibody, Pparbp antibody, l11Jus15 antibody, RGD1559552 antibody, mediator complex subunit 1 antibody, calcitonin-related polypeptide beta antibody, Mediator complex subunit 1 antibody, mediator of RNA polymerase II transcription subunit 1 antibody, MED1 antibody, CALCB antibody, med1 antibody, Med1 antibody
- 背景
-
Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (PubMed:10406464, PubMed:11867769, PubMed:12037571, PubMed:12218053, PubMed:12556447, PubMed:14636573, PubMed:15340084, PubMed:15471764, PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).
Aliases: Activator-recruited cofactor 205 kDa component antibody, ARC205 antibody, CRSP1 antibody, CRSP200 antibody, DRIP205 antibody, DRIP230 antibody, MED1 antibody, MED1_HUMAN antibody, Mediator complex subunit 1 antibody, Mediator of RNA polymerase II transcription subunit 1 antibody, p53 regulatory protein RB18A antibody, PBP antibody, Peroxisome proliferator-activated receptor-binding protein antibody, PPAR binding protein antibody, PPAR-binding protein antibody, PPARBP antibody, PPARGBP antibody, RB18A antibody, Thyroid hormone receptor-associated protein complex 220 kDa component antibody, Thyroid receptor-interacting protein 2 antibody, TR-interacting protein 2 antibody, Trap220 antibody, TRIP-2 antibody, TRIP2 antibody, Vitamin D receptor-interacting protein complex component DRIP205 antibody
- UniProt
- Q15648
- 途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
-