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MAML1 抗体 (AA 1-45) (FITC)

MAML1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7159035
发货至: 中国
  • 抗原 See all MAML1 抗体
    MAML1 (Mastermind-Like 1 (MAML1))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-45
    适用
    • 29
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 28
    • 1
    • 1
    克隆类型
    • 30
    多克隆
    标记
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    This MAML1 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Mastermind-like protein 1 protein (1-45AA)
    亚型
    IgG
    Top Product
    Discover our top product MAML1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MAML1 (Mastermind-Like 1 (MAML1))
    别名
    MAML1 (MAML1 产品)
    别名
    mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody
    背景

    Background: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.

    Aliases: Mam-1 antibody, Mam1 antibody, MAML 1 antibody, Maml1 antibody, MAML1_HUMAN antibody, Mastermind like 1 antibody, Mastermind-like protein 1 antibody

    UniProt
    Q92585
    途径
    Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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