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LRP6 抗体 (AA 20-150)

LRP6 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7158577
发货至: 中国
  • 抗原 See all LRP6 抗体
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    抗原表位
    • 22
    • 21
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    AA 20-150
    适用
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    宿主
    • 60
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    克隆类型
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    多克隆
    标记
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    This LRP6 antibody is un-conjugated
    应用范围
    • 50
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    • 17
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    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Low-density lipoprotein receptor-related protein 6 protein (20-150AA)
    亚型
    IgG
    Top Product
    Discover our top product LRP6 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    别名
    LRP6 (LRP6 产品)
    别名
    lrp6-A antibody, Xlrp6 antibody, adcad2 antibody, lrp6 antibody, LRP6 antibody, ADCAD2 antibody, C030016K15Rik antibody, Cd antibody, Gw antibody, LDL receptor related protein 6 antibody, LDL receptor related protein 6 L homeolog antibody, LDL receptor related protein 6 S homeolog antibody, low density lipoprotein receptor-related protein 6 antibody, low-density lipoprotein receptor-related protein 6 antibody, LRP6 antibody, lrp6.L antibody, lrp6.S antibody, lrp6 antibody, Lrp6 antibody, LOC590395 antibody
    背景

    Background: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).

    Aliases: ADCAD2 antibody, C030016K15Rik antibody, Cd antibody, FLJ90062 antibody, FLJ90421 antibody, LDL receptor related protein 6 antibody, Low density lipoprotein receptor related protein 6 antibody, Low-density lipoprotein receptor-related protein 6 antibody, LRP-6 antibody, LRP6 antibody, LRP6_HUMAN antibody, OTTHUMP00000238979 antibody, OTTHUMP00000238980 antibody, OTTHUMP00000238982 antibody, STHAG7 antibody

    UniProt
    O75581
    途径
    WNT signaling, Tube Formation
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