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LRP4 抗体 (AA 1500-1725)

LRP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7158575
发货至: 中国
  • 抗原 See all LRP4 抗体
    LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))
    抗原表位
    • 11
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1500-1725
    适用
    • 24
    • 20
    • 11
    • 2
    宿主
    • 19
    • 16
    • 1
    • 1
    克隆类型
    • 21
    • 16
    多克隆
    标记
    • 14
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LRP4 antibody is un-conjugated
    应用范围
    • 24
    • 16
    • 14
    • 13
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Low-density lipoprotein receptor-related protein 4 protein (1500-1725AA)
    亚型
    IgG
    Top Product
    Discover our top product LRP4 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))
    别名
    LRP4 (LRP4 产品)
    别名
    CLSS antibody, LRP-4 antibody, LRP10 antibody, MEGF7 antibody, SOST2 antibody, Megf7 antibody, 6430526J12Rik antibody, D230026E03 antibody, mdig antibody, LRP4 antibody, lrp10 antibody, megf7 antibody, LDL receptor related protein 4 antibody, low density lipoprotein receptor-related protein 4 antibody, LRP4 antibody, Lrp4 antibody, lrp4 antibody
    背景

    Background: Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Alternatively, may be involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. More generally, has been proposed to function as a cell surface endocytic receptor binding and internalizing extracellular ligands for degradation by lysosomes.

    Aliases: KIAA0816 antibody, LDLR dan antibody, Low density lipoprotein receptor related protein 4 antibody, Low-density lipoprotein receptor-related protein 4 antibody, LRP-4 antibody, LRP10 antibody, Lrp4 antibody, LRP4_HUMAN antibody, MEGF7 antibody, Multiple epidermal growth factor like domains 7 antibody, Multiple epidermal growth factor-like domains 7 antibody

    UniProt
    O75096
    途径
    Skeletal Muscle Fiber Development
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