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L3MBTL1 抗体 (AA 513-752)

L3MBTL1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7158005
发货至: 中国
  • 抗原 See all L3MBTL1 抗体
    L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 513-752
    适用
    • 18
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    宿主
    • 17
    • 2
    • 1
    克隆类型
    • 18
    • 1
    • 1
    多克隆
    标记
    • 19
    • 1
    This L3MBTL1 antibody is un-conjugated
    应用范围
    • 15
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Lethal(3)malignant brain tumor-like protein 1 protein (513-752AA)
    亚型
    IgG
    Top Product
    Discover our top product L3MBTL1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
    别名
    L3MBTL1 (L3MBTL1 产品)
    别名
    C630004G01 antibody, L3mbtl antibody, mKIAA0681 antibody, H-L(3)MBT antibody, L3MBTL antibody, ZC2HC3 antibody, dJ138B7.3 antibody, RGD1307316 antibody, l(3)mbt-like (Drosophila) antibody, L3MBTL1, histone methyl-lysine binding protein antibody, l(3)mbt-like 1 (Drosophila) antibody, L3mbtl1 antibody, L3MBTL1 antibody
    背景

    Background: Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a \\\'reader\\\' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at \\\'Lys-26\\\' (H1bK26me1 and H1bK26me2) and histone H4 at \\\'Lys-20\\\' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at \\\'Lys-382\\\', leading to repress p53/TP53-target genes. Also recognizes and binds RB1/RB monomethylated at \\\'Lys-860\\\'. Participates in the ETV6-mediated repression. Probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis.

    Aliases: dJ138B7.3 antibody, H-L(3)MBT antibody, H-l(3)mbt protein antibody, KIAA0681 antibody, L(3)mbt protein homolog antibody, L(3)mbt-like antibody, L3MBT antibody, L3MBTL antibody, L3MBTL1 antibody, Lethal (3) malignant brain tumor l(3 antibody, Lethal(3)malignant brain tumor-like protein 1 antibody, LMBL1_HUMAN antibody, RGD1307316 antibody, ZC2HC3 antibody

    UniProt
    Q9Y468
    途径
    Chromatin Binding
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