L3MBTL1 抗体 (AA 513-752)
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- 抗原 See all L3MBTL1 抗体
- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
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抗原表位
- AA 513-752
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This L3MBTL1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Lethal(3)malignant brain tumor-like protein 1 protein (513-752AA)
- 亚型
- IgG
- Top Product
- Discover our top product L3MBTL1 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
- 别名
- L3MBTL1 (L3MBTL1 产品)
- 别名
- C630004G01 antibody, L3mbtl antibody, mKIAA0681 antibody, H-L(3)MBT antibody, L3MBTL antibody, ZC2HC3 antibody, dJ138B7.3 antibody, RGD1307316 antibody, l(3)mbt-like (Drosophila) antibody, L3MBTL1, histone methyl-lysine binding protein antibody, l(3)mbt-like 1 (Drosophila) antibody, L3mbtl1 antibody, L3MBTL1 antibody
- 背景
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Background: Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a \\\'reader\\\' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at \\\'Lys-26\\\' (H1bK26me1 and H1bK26me2) and histone H4 at \\\'Lys-20\\\' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at \\\'Lys-382\\\', leading to repress p53/TP53-target genes. Also recognizes and binds RB1/RB monomethylated at \\\'Lys-860\\\'. Participates in the ETV6-mediated repression. Probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis.
Aliases: dJ138B7.3 antibody, H-L(3)MBT antibody, H-l(3)mbt protein antibody, KIAA0681 antibody, L(3)mbt protein homolog antibody, L(3)mbt-like antibody, L3MBT antibody, L3MBTL antibody, L3MBTL1 antibody, Lethal (3) malignant brain tumor l(3 antibody, Lethal(3)malignant brain tumor-like protein 1 antibody, LMBL1_HUMAN antibody, RGD1307316 antibody, ZC2HC3 antibody
- UniProt
- Q9Y468
- 途径
- Chromatin Binding
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