KLF1 抗体 (AA 1-362) (FITC)
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- 抗原 See all KLF1 抗体
- KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
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抗原表位
- AA 1-362
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KLF1 antibody is conjugated to FITC
- 应用范围
- 请咨询
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Krueppel-like factor 1 protein (1-362AA)
- 亚型
- IgG
- Top Product
- Discover our top product KLF1 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
- 别名
- KLF1 (KLF1 产品)
- 别名
- KLF1 antibody, EKLF antibody, HBFQTL6 antibody, INLU antibody, Eklf antibody, Nan antibody, Kruppel-like factor 1 (erythroid) antibody, Kruppel like factor 1 antibody, KLF-4 antibody, KLF1 antibody, Klf1 antibody
- 背景
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Background: Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.
Aliases: CDAN4 antibody, EKLF antibody, EKLF PEN antibody, Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor) antibody, Erythroid krueppel-like transcription factor antibody, Erythroid Kruppel like factor antibody, Erythroid specific transcription factor EKLF antibody, HBFQTL6 antibody, Human erythroid-specific transcription factor EKLF mRNA complete cds antibody, INLU antibody, Klf1 antibody, KLF1_HUMAN antibody, Krueppel-like factor 1 antibody, Kruppel like factor 1 (erythroid) antibody
- UniProt
- Q13351
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