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KLF1 抗体 (AA 1-362) (FITC)

KLF1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7157705
发货至: 中国
  • 抗原 See all KLF1 抗体
    KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
    抗原表位
    • 9
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-362
    适用
    • 45
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    宿主
    • 34
    • 11
    • 1
    克隆类型
    • 36
    • 11
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLF1 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Krueppel-like factor 1 protein (1-362AA)
    亚型
    IgG
    Top Product
    Discover our top product KLF1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
    别名
    KLF1 (KLF1 产品)
    别名
    KLF1 antibody, EKLF antibody, HBFQTL6 antibody, INLU antibody, Eklf antibody, Nan antibody, Kruppel-like factor 1 (erythroid) antibody, Kruppel like factor 1 antibody, KLF-4 antibody, KLF1 antibody, Klf1 antibody
    背景

    Background: Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.

    Aliases: CDAN4 antibody, EKLF antibody, EKLF PEN antibody, Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor) antibody, Erythroid krueppel-like transcription factor antibody, Erythroid Kruppel like factor antibody, Erythroid specific transcription factor EKLF antibody, HBFQTL6 antibody, Human erythroid-specific transcription factor EKLF mRNA complete cds antibody, INLU antibody, Klf1 antibody, KLF1_HUMAN antibody, Krueppel-like factor 1 antibody, Kruppel like factor 1 (erythroid) antibody

    UniProt
    Q13351
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