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KIF14 抗体 (AA 261-531) (HRP)

KIF14 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7157598
发货至: 中国
  • 抗原 See all KIF14 抗体
    KIF14 (Kinesin Family Member 14 (KIF14))
    抗原表位
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 261-531
    适用
    • 23
    • 4
    • 4
    • 1
    宿主
    • 22
    • 1
    克隆类型
    • 23
    多克隆
    标记
    • 12
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIF14 antibody is conjugated to HRP
    应用范围
    • 12
    • 9
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Kinesin-like protein KIF14 protein (261-531AA)
    亚型
    IgG
    Top Product
    Discover our top product KIF14 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    KIF14 (Kinesin Family Member 14 (KIF14))
    别名
    KIF14 (KIF14 产品)
    别名
    wu:fi16h07 antibody, si:dkey-39e8.3 antibody, KIF14 antibody, D1Ertd367e antibody, E130203M01 antibody, kinesin family member 14 antibody, kinesin-like protein KIF14 antibody, KIF14 antibody, kif14 antibody, LOC100641544 antibody, Kif14 antibody
    背景

    Background: Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).

    Aliases: KIAA0042 antibody, KIF 14 antibody, KIF14 antibody, KIF14_HUMAN antibody, Kinesin Family Member 14 antibody, Kinesin like protein KIF14 antibody, Kinesin-like protein KIF14 antibody, MGC142302 antibody

    UniProt
    Q15058
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