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KSR2 抗体 (AA 159-296)

KSR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7157558
发货至: 中国
  • 抗原 See all KSR2 抗体
    KSR2 (Kinase Suppressor of Ras 2 (KSR2))
    抗原表位
    • 8
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 159-296
    适用
    • 46
    • 15
    宿主
    • 40
    • 6
    克隆类型
    • 43
    • 3
    多克隆
    标记
    • 20
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KSR2 antibody is un-conjugated
    应用范围
    • 35
    • 30
    • 15
    • 13
    • 8
    • 6
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Kinase suppressor of Ras 2 protein (159-296AA)
    亚型
    IgG
    Top Product
    Discover our top product KSR2 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    KSR2 (Kinase Suppressor of Ras 2 (KSR2))
    别名
    KSR2 (KSR2 产品)
    别名
    kinase suppressor of ras 2 antibody, KSR2 antibody, Ksr2 antibody
    背景

    Background: Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

    Aliases: FLJ25965 antibody, hKSR 2 antibody, hKSR2 antibody, Kinase suppressor of Ras 2 antibody, KSR 2 antibody, Ksr2 antibody, KSR2_HUMAN antibody

    UniProt
    Q6VAB6
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