KHDRBS2 抗体 (AA 1-349) (Biotin)
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- 抗原 See all KHDRBS2 抗体
- KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
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抗原表位
- AA 1-349
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KHDRBS2 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human KH domain-containing, RNA-binding, signal transduction-associated protein 2 protein (1-349AA)
- 亚型
- IgG
- Top Product
- Discover our top product KHDRBS2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
- 别名
- KHDRBS2 (KHDRBS2 产品)
- 别名
- slm1 antibody, slm-1 antibody, MGC145973 antibody, ba535f17.1 antibody, zgc:153588 antibody, SLM-1 antibody, SLM1 antibody, bA535F17.1 antibody, 6330586C16Rik antibody, Slim1 antibody, Slm1 antibody, KH RNA binding domain containing, signal transduction associated 2 antibody, KH domain containing, RNA binding, signal transduction associated 2 antibody, KHDRBS2 antibody, khdrbs2 antibody, Khdrbs2 antibody
- 背景
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Background: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.
Aliases: KH domain containing, RNA binding, signal transduction associated protein 2 antibody, 6330586C16Rik antibody, bA535F17.1 antibody, FLJ38664 antibody, hSLM 1 antibody, hSLM-1 antibody, KH domain containing, RNA binding, signal transduction associated 2 antibody, KH domain-containing antibody, KHDR2_HUMAN antibody, khdrbs2 antibody, MGC26664 antibody, RNA-binding antibody, Sam68 like mammalian protein 1 antibody, Sam68-like mammalian protein 1 antibody, signal transduction-associated protein 2 antibody, SLM 1 antibody, SLM-1 antibody, SLM1 antibody
- UniProt
- Q5VWX1
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