KLHL22 抗体 (AA 2-300)
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- 抗原 See all KLHL22 抗体
- KLHL22 (Kelch-Like 22 (KLHL22))
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抗原表位
- AA 2-300
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KLHL22 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Kelch-like protein 22 protein (2-300AA)
- 亚型
- IgG
- Top Product
- Discover our top product KLHL22 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:2000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- KLHL22 (Kelch-Like 22 (KLHL22))
- 别名
- KLHL22 (KLHL22 产品)
- 别名
- 2610318I18Rik antibody, Kelchl antibody, KELCHL antibody, RGD1306288 antibody, kelch-like 22 antibody, kelch like family member 22 antibody, kelch-like family member 22 antibody, Klhl22 antibody, KLHL22 antibody
- 背景
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Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
Aliases: KLHL22Kelch-like protein 22 antibody
- UniProt
- Q53GT1
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