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KLHL12 抗体 (AA 1-220) (Biotin)

KLHL12 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7157268
发货至: 中国
  • 抗原 See all KLHL12 抗体
    KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-220
    适用
    • 38
    • 28
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    宿主
    • 48
    • 4
    • 1
    克隆类型
    • 50
    • 3
    多克隆
    标记
    • 20
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLHL12 antibody is conjugated to Biotin
    应用范围
    • 41
    • 20
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Kelch-like protein 12 protein (1-220AA)
    亚型
    IgG
    Top Product
    Discover our top product KLHL12 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
    别名
    KLHL12 (KLHL12 产品)
    别名
    zgc:92570 antibody, wu:fi60g03 antibody, C3ip1 antibody, C3IP1 antibody, DKIR antibody, hDKIR antibody, Ski2 like RNA helicase antibody, kelch like family member 12 L homeolog antibody, kelch like family member 12 antibody, kelch-like family member 12 antibody, kelch-like 12 antibody, SKIV2L antibody, klhl12.L antibody, KLHL12 antibody, klhl12 antibody, Klhl12 antibody
    背景

    Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). As part of the BCR(KLHL12) complex, also acts as a negative regulator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3. The BCR(KLHL12) complex also mediates polyubiquitination of DRD4, without leading to degradation of DRD4.

    Aliases: C3IP1 antibody, CUL3 interacting protein 1 antibody, CUL3-interacting protein 1 antibody, DKIR antibody, DKIR homolog antibody, FLJ27152 antibody, hDKIR antibody, Kelch like 12 (Drosophila) antibody, Kelch like 12 antibody, Kelch like 12 variant antibody, Kelch like protein 12 antibody, Kelch like protein C3IP1 antibody, kelch-like family member 12 antibody, Kelch-like protein 12 antibody, KLH12_HUMAN antibody, KLHL 12 antibody, klhl12 antibody, OTTHUMP00000038799 antibody

    UniProt
    Q53G59
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