ISCU 抗体 (AA 1-167)
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- 抗原 See all ISCU 抗体
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
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抗原表位
- AA 1-167
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ISCU antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Iron-sulfur cluster assembly enzyme ISCU, mitochondrial protein (1-167AA)
- 亚型
- IgG
- Top Product
- Discover our top product ISCU Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- 别名
- ISCU (ISCU 产品)
- 别名
- nifun antibody, zC191D15.3 antibody, si:ch211-191d15.3 antibody, 2310020H20Rik antibody, HML antibody, ISU2 antibody, NIFU antibody, NIFUN antibody, hnifU antibody, RGD1309562 antibody, AA407971 antibody, Nifu antibody, Nifun antibody, iron-sulfur cluster assembly enzyme ISCU, mitochondrial antibody, iron-sulfur cluster assembly enzyme antibody, iron-sulfur cluster assembly enzyme a antibody, LOC409130 antibody, ISCU antibody, iscua antibody, Iscu antibody
- 背景
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Background: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (PubMed:11060020). First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU. In a second step, the cluster is released from ISCU, transferred to a glutaredoxin GLRX5, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISCU depends on the function of the cysteine desulfurase complex NFS1-LYRM4/ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH (By similarity).
Aliases: 2310020H20Rik antibody, HML antibody, hnifU antibody, Iron sulfur cluster assembly enzyme ISCU mitochondrial antibody, Iron sulfur cluster scaffold homolog (E. coli) antibody, Iron sulfur cluster scaffold homolog antibody, Iron-sulfur cluster assembly enzyme ISCU antibody, Iscu antibody, IscU iron sulfur cluster scaffold homolog antibody, ISCU_HUMAN antibody, ISU2 antibody, MGC74517 antibody, mitochondrial antibody, NIFU antibody, NifU like N terminal domain containing antibody, NifU like N terminal domain containing protein antibody, NifU like protein antibody, NifU-like N-terminal domain-containing protein antibody, NifU-like protein antibody, NIFUN antibody, Nitrogen fixation cluster like antibody, OTTHUMP00000238760 antibody, OTTHUMP00000238761 antibody, OTTHUMP00000238762 antibody, OTTHUMP00000238764 antibody, OTTHUMP00000238765 antibody
- UniProt
- Q9H1K1
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