Inversin 抗体 (AA 1-101) (FITC)
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- 抗原 See all Inversin (INVS) 抗体
- Inversin (INVS)
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抗原表位
- AA 1-101
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Inversin antibody is conjugated to FITC
- 应用范围
- 请咨询
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Inversin protein (1-101AA)
- 亚型
- IgG
- Top Product
- Discover our top product INVS Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Inversin (INVS)
- 别名
- INVS (INVS 产品)
- 背景
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Background: Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity).
Aliases: INVS antibody, INV antibody, NPHP2 antibody, Inversin antibody, Inversion of embryo turning homolog antibody, Nephrocystin-2 antibody
- UniProt
- Q9Y283
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