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Inversin 抗体 (AA 1-101) (Biotin)

INVS 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7157009
发货至: 中国
  • 抗原 See all Inversin (INVS) 抗体
    Inversin (INVS)
    抗原表位
    • 15
    • 4
    • 1
    • 1
    AA 1-101
    适用
    • 22
    • 16
    • 1
    宿主
    • 21
    • 1
    克隆类型
    • 22
    多克隆
    标记
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Inversin antibody is conjugated to Biotin
    应用范围
    • 19
    • 13
    • 13
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Inversin protein (1-101AA)
    亚型
    IgG
    Top Product
    Discover our top product INVS Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Inversin (INVS)
    别名
    INVS (INVS 产品)
    别名
    invs-a antibody, INVS antibody, MGC140477 antibody, inv antibody, NPH2 antibody, NPHP2 antibody, INV antibody, Nphp2 antibody, RGD1563359 antibody, wu:fe47e11 antibody, inversin S homeolog antibody, inversin antibody, Inversin antibody, invs.S antibody, INVS antibody, Bm1_38710 antibody, PTRG_09181 antibody, EAMY_RS33690 antibody, LOAG_11716 antibody, invs antibody, Invs antibody
    背景

    Background: Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity).

    Aliases: INVS antibody, INV antibody, NPHP2 antibody, Inversin antibody, Inversion of embryo turning homolog antibody, Nephrocystin-2 antibody

    UniProt
    Q9Y283
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