EBI3 抗体 (AA 21-227)
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- 抗原 See all EBI3 (IL-27b) 抗体
- EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
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抗原表位
- AA 21-227
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EBI3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Interleukin-27 subunit beta protein (21-227AA)
- 亚型
- IgG
- Top Product
- Discover our top product IL-27b Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
- 别名
- EBI3 (IL-27b 产品)
- 别名
- IL-27B antibody, IL27B antibody, EBI3 antibody, il-27rb antibody, si:dkey-97a13.4 antibody, EBI-3 antibody, IL-27 antibody, Epstein-Barr virus induced 3 antibody, Epstein-Barr virus induced gene 3 antibody, EBI3 antibody, ebi3 antibody, Ebi3 antibody
- 物质类
- Viral Protein
- 背景
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Background: Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
Aliases: cytokine receptor antibody, EBI3 antibody, EBV induced gene 3 protein antibody, EBV-induced gene 3 protein antibody, Epstein Barr virus induced 3 antibody, Epstein Barr virus induced gene 3 antibody, Epstein Barr virus induced gene 3 protein antibody, Epstein-Barr virus-induced gene 3 protein antibody, IL 27 subunit beta antibody, IL 27B antibody, IL-27 subunit beta antibody, IL-27B antibody, IL27 subunit antibody, IL27 subunit beta antibody, IL27B antibody, IL27B_HUMAN antibody, IL35 subunit antibody, interleukin 27 subunit beta antibody, Interleukin-27 subunit beta antibody
- UniProt
- Q14213
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