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AIM2 抗体 (AA 81-326)

AIM2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7156703
发货至: 中国
  • 抗原 See all AIM2 抗体
    AIM2 (Absent in Melanoma 2 (AIM2))
    抗原表位
    • 16
    • 11
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-326
    适用
    • 72
    • 25
    • 19
    • 3
    • 3
    • 1
    宿主
    • 60
    • 11
    • 2
    克隆类型
    • 65
    • 8
    多克隆
    标记
    • 36
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIM2 antibody is un-conjugated
    应用范围
    • 61
    • 32
    • 32
    • 21
    • 13
    • 13
    • 10
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Interferon-inducible protein AIM2 protein (81-326AA)
    亚型
    IgG
    Top Product
    Discover our top product AIM2 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    AIM2 (Absent in Melanoma 2 (AIM2))
    别名
    AIM2 (AIM2 产品)
    别名
    AIM2 antibody, PYHIN4 antibody, Gm1313 antibody, Ifi210 antibody, absent in melanoma 2 antibody, AIM2 antibody, Aim2 antibody
    背景

    Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

    Aliases: Absent in melanoma 2 antibody, AIM 2 antibody, Aim2 antibody, AIM2_HUMAN antibody, Interferon-inducible protein AIM2 antibody, OTTHUMP00000035296 antibody, PYHIN4 antibody

    UniProt
    O14862
    途径
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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