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IFIT1 抗体 (AA 1-181)

IFIT1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7156663
发货至: 中国
  • 抗原 See all IFIT1 抗体
    IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))
    抗原表位
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-181
    适用
    • 28
    • 12
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 24
    • 4
    克隆类型
    • 26
    • 2
    多克隆
    标记
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFIT1 antibody is un-conjugated
    应用范围
    • 18
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Interferon-induced protein with tetratricopeptide repeats 1 protein (1-181AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))
    别名
    IFIT1 (IFIT1 产品)
    别名
    C56 antibody, G10P1 antibody, IFI-56 antibody, IFI-56K antibody, IFI56 antibody, IFIT-1 antibody, IFNAI1 antibody, ISG56 antibody, P56 antibody, RNM561 antibody, Ifi56 antibody, Garg16 antibody, DKFZp469C2331 antibody, interferon induced protein with tetratricopeptide repeats 1 antibody, interferon-induced protein with tetratricopeptide repeats 1 antibody, IFIT1 antibody, Ifit1 antibody, LOC488947 antibody, ifit1 antibody, LOC100058990 antibody, LOC100139670 antibody, LOC100475782 antibody
    背景

    Background: Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5\\\'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2\\\'-O-methylation of the 5\\\' cap and bear a 5\\\'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2\\\'-O-methylase for their mRNAs or by stealing host cap containing the 2\\\'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.

    Aliases: C56 antibody, G10P1 antibody, GARG 16 antibody, GARG16 antibody, IFI 56 antibody, IFI 56K antibody, IFI-56K antibody, IFI56 antibody, IFIT-1 antibody, Ifit1 antibody, IFIT1_HUMAN antibody, IFNAI1 antibody, Interferon alpha inducible protein (MW 56kD) antibody, Interferon induced 56 kDa protein antibody, Interferon induced protein 56 antibody, Interferon inducible mRNA 561 antibody, Interferon-induced 56 kDa protein antibody, Interferon-induced protein with tetratricopeptide repeats 1 antibody, ISG56 antibody, OTTHUMP00000020062 antibody, P56 antibody, RNM561 antibody

    UniProt
    P09914
    途径
    Hepatitis C
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