IRF7 抗体 (AA 131-289) (HRP)
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- 抗原 See all IRF7 抗体
- IRF7 (Interferon Regulatory Factor 7 (IRF7))
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抗原表位
- AA 131-289
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRF7 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Interferon regulatory factor 7 protein (131-289AA)
- 亚型
- IgG
- Top Product
- Discover our top product IRF7 Primary Antibody
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anti-Interferon Regulatory Factor 7 (IRF7) (pSer471), (pSer472) antibody
IRF7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 401-503) antibodyIRF7 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 131-289) antibodyIRF7 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 1-150), (N-Term) antibodyIRF7 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) antibodyIRF7 适用: 人 WB, IF (cc) 宿主: 兔 Monoclonal 2A1 unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 257-516) antibodyIRF7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (C-Term) antibodyIRF7 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 35-84) antibodyIRF7 适用: 人, 小鼠, 大鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 1-150) antibodyIRF7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (N-Term) antibodyIRF7 适用: 人, 小鼠, 大鼠, Pig, 斑马鱼, 马, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- IRF7 (Interferon Regulatory Factor 7 (IRF7))
- 别名
- IRF7 (IRF7 产品)
- 别名
- wu:fl24c03 antibody, zgc:66043 antibody, zgc:77947 antibody, IRF7 antibody, irf7 antibody, IRF-7H antibody, IRF7A antibody, IRF7B antibody, IRF7C antibody, IRF7H antibody, interferon regulatory factor 7 antibody, irf7 antibody, IRF7 antibody, Irf7 antibody
- 背景
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Background: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase. Exists in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, becomes phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization where along with other coactivators it can activate transcription of the type I IFN and ISG genes. Can also play a role in regulating adaptive immune responses by inducing PSMB9/LMP2 expression, either directly or through induction of IRF1. Binds to the Q promoter (Qp) of EBV nuclear antigen 1 a (EBNA1) and may play a role in the regulation of EBV latency. Can activate distinct gene expression programs in macrophages and regulate the anti-tumor properties of primary macrophages.
Aliases: IMD39 antibody, Interferon regulatory factor 7 antibody, Interferon regulatory factor 7H antibody, IRF 7 antibody, IRF 7A antibody, IRF 7H antibody, IRF-7 antibody, IRF7 antibody, IRF7_HUMAN antibody, IRF7A antibody, IRF7B antibody, IRF7C antibody, IRF7H antibody
- UniProt
- Q92985
- 途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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