IL28B 抗体 (AA 22-196)
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- 抗原 See all IL28B 抗体
- IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
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抗原表位
- AA 22-196
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL28B antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Interferon lambda-3 protein (22-196AA)
- 亚型
- IgG
- Top Product
- Discover our top product IL28B Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
- 别名
- IFNL3 (IL28B 产品)
- 别名
- Il28b antibody, IFL-1 antibody, IL-28B antibody, INF-alpha antibody, INF-lambda antibody, Il28 antibody, IL28B antibody, IL28C antibody, interferon, lambda 3 antibody, interferon lambda 3 antibody, Ifnl3 antibody, IFNL3 antibody
- 背景
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Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Aliases: Cytokine ZCYTO22 antibody, IFN-lambda-3 antibody, IFN-lambda-4 antibody, IL-28B antibody, IL-28C antibody, IL28B antibody, IL28B_HUMAN antibody, IL28C antibody, Interferon lambda-3 antibody, Interferon lambda-4 antibody, interleukin 28B (interferon, lambda 3) antibody, Interleukin 28C antibody, Interleukin-28B antibody, Interleukin-28C antibody
- UniProt
- Q8IZI9
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