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IL28B 抗体 (AA 22-196)

IL28B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7156612
发货至: 中国
  • 抗原 See all IL28B 抗体
    IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
    抗原表位
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-196
    适用
    • 33
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 30
    • 4
    • 1
    克隆类型
    • 30
    • 5
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL28B antibody is un-conjugated
    应用范围
    • 26
    • 16
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Interferon lambda-3 protein (22-196AA)
    亚型
    IgG
    Top Product
    Discover our top product IL28B Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
    别名
    IFNL3 (IL28B 产品)
    别名
    Il28b antibody, IFL-1 antibody, IL-28B antibody, INF-alpha antibody, INF-lambda antibody, Il28 antibody, IL28B antibody, IL28C antibody, interferon, lambda 3 antibody, interferon lambda 3 antibody, Ifnl3 antibody, IFNL3 antibody
    背景

    Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

    Aliases: Cytokine ZCYTO22 antibody, IFN-lambda-3 antibody, IFN-lambda-4 antibody, IL-28B antibody, IL-28C antibody, IL28B antibody, IL28B_HUMAN antibody, IL28C antibody, Interferon lambda-3 antibody, Interferon lambda-4 antibody, interleukin 28B (interferon, lambda 3) antibody, Interleukin 28C antibody, Interleukin-28B antibody, Interleukin-28C antibody

    UniProt
    Q8IZI9
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