ITGA7 抗体 (AA 175-283)
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- 抗原 See all ITGA7 抗体
- ITGA7 (Integrin, alpha 7 (ITGA7))
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抗原表位
- AA 175-283
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ITGA7 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Integrin alpha-7 protein (175-283AA)
- 亚型
- IgG
- Top Product
- Discover our top product ITGA7 Primary Antibody
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- 应用备注
- Recommended dilution: IF:1:200-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ITGA7 (Integrin, alpha 7 (ITGA7))
- 别名
- ITGA7 (ITGA7 产品)
- 别名
- [a]7 antibody, alpha7 antibody, integrin alpha 7 antibody, integrin subunit alpha 7 antibody, Itga7 antibody, ITGA7 antibody
- 背景
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Background: Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
Aliases: alpha 7 antibody, FLJ25220 antibody, Integrin alpha 7 antibody, Integrin alpha 7 chain antibody, Integrin alpha 7 heavy chain antibody, Integrin alpha 7 light chain antibody, Integrin alpha-7 70 kDa form antibody, ITA7_HUMAN antibody, ITGA 7 antibody, Itga7 antibody
- UniProt
- Q13683
- 途径
- Integrin Complex
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