Importin 11 抗体 (AA 1-270) (Biotin)
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- 抗原 See all Importin 11 (IPO11) 抗体
- Importin 11 (IPO11)
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抗原表位
- AA 1-270
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Importin 11 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Importin-11 protein (1-270AA)
- 亚型
- IgG
- Top Product
- Discover our top product IPO11 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Importin 11 (IPO11)
- 别名
- IPO11 (IPO11 产品)
- 别名
- MGC83107 antibody, IPO11 antibody, slrn antibody, ranbp11 antibody, RanBP11 antibody, 1700081H05Rik antibody, 2510001A17Rik antibody, AI314624 antibody, AW555235 antibody, E330021B14Rik antibody, Ranbp11 antibody, importin 11 S homeolog antibody, importin 11 antibody, importin-11 antibody, ipo11.S antibody, ipo11 antibody, IPO11 antibody, AFUA_1G03590 antibody, BDBG_04626 antibody, LOC100162908 antibody, Ipo11 antibody
- 背景
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Background: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).
Aliases: Imp11 antibody, Importin 11 antibody, Importin-11 antibody, IPO11 antibody, IPO11_HUMAN antibody, Ran binding protein 11 antibody, Ran-binding protein 11 antibody, RanBP11 antibody, SLRN antibody, Synleurin antibody
- UniProt
- Q9UI26
- 途径
- Protein targeting to Nucleus
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