电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

KPNA1 抗体 (AA 8-538) (HRP)

KPNA1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7156129
发货至: 中国
  • 抗原 See all KPNA1 抗体
    KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
    抗原表位
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 8-538
    适用
    • 36
    • 18
    • 17
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 26
    • 8
    • 1
    • 1
    克隆类型
    • 30
    • 6
    多克隆
    标记
    • 26
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KPNA1 antibody is conjugated to HRP
    应用范围
    • 26
    • 13
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Importin subunit alpha-5 protein (8-538AA)
    亚型
    IgG
    Top Product
    Discover our top product KPNA1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
    别名
    KPNA1 (KPNA1 产品)
    别名
    IPOA5 antibody, NPI-1 antibody, RCH2 antibody, SRP1 antibody, AW494490 antibody, NPI1 antibody, Rch2 antibody, mSRP1 antibody, si:ch211-161h7.7 antibody, karyopherin subunit alpha 1 antibody, importin alpha-1 subunit antibody, karyopherin (importin) alpha 1 antibody, karyopherin alpha 1 (importin alpha 5) antibody, KPNA1 antibody, Kpna1 antibody, EHI_124900 antibody, kpna1 antibody
    背景

    Background: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

    Aliases: IMA5_HUMAN antibody, Importin alpha 1 subunit antibody, Importin alpha 5 antibody, Importin alpha S1 antibody, Importin subunit alpha-5, N-terminally processed antibody, IPO A5 antibody, IPOA 5 antibody, IPOA5 antibody, Karyopherin alpha 1 antibody, Karyopherin alpha 1 subunit antibody, Karyopherin subunit alpha-1 antibody, KPNA 1 antibody, KPNA1 antibody, mSRP 1 antibody, mSRP1 antibody, NPI 1 antibody, NPI-1 antibody, NPI1 antibody, Nucleoprotein interactor 1 antibody, RAG cohort protein 2 antibody, RCH 2 antibody, RCH2 antibody, Recombination activating gene cohort 2 antibody, SRP 1 antibody, SRP1 beta antibody, SRP1-beta antibody

    UniProt
    P52294
    途径
    M Phase, Protein targeting to Nucleus
You are here:
客服