IGKC 抗体 (AA 1-107)
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- 抗原 See all IGKC products
- IGKC (Immunoglobulin kappa Constant (IGKC))
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抗原表位
- AA 1-107
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IGKC antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Immunoglobulin kappa constant protein (1-107AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- IGKC (Immunoglobulin kappa Constant (IGKC))
- 别名
- IGKC (IGKC 产品)
- 别名
- HCAK1 antibody, IGKCD antibody, Km antibody, IGKC antibody, Igk-C antibody, immunoglobulin kappa constant antibody, immunoglobulin kappa constant L homeolog antibody, IGKC antibody, LOC708048 antibody, igkc antibody, igkc.L antibody, Igkc antibody
- 背景
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Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Aliases: IGKCImmunoglobulin kappa constant antibody, Ig kappa chain C region antibody, Ig kappa chain C region AG antibody, Ig kappa chain C region CUM antibody, Ig kappa chain C region EU antibody, Ig kappa chain C region OU antibody, Ig kappa chain C region ROY antibody, Ig kappa chain C region TI antibody
- UniProt
- P01834
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