HIPK3 抗体 (AA 841-1130) (HRP)
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- 抗原 See all HIPK3 抗体
- HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
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抗原表位
- AA 841-1130
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HIPK3 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Homeodomain-interacting protein kinase 3 protein (841-1130AA)
- 亚型
- IgG
- Top Product
- Discover our top product HIPK3 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
- 别名
- HIPK3 (HIPK3 产品)
- 别名
- HIPK3 antibody, pky antibody, yak1 antibody, dyrk6 antibody, fist3 antibody, MGC145460 antibody, DYRK6 antibody, FIST3 antibody, PKY antibody, YAK1 antibody, ANPK antibody, homeodomain interacting protein kinase 3 antibody, homeodomain interacting protein kinase 3 L homeolog antibody, HIPK3 antibody, hipk3.L antibody, hipk3 antibody, Hipk3 antibody
- 背景
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Background: Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
Aliases: Androgen receptor interacting nuclear protein kinase antibody, Androgen receptor-interacting nuclear protein kinase antibody, ANPK antibody, DYRK6 antibody, Fas interacting serine/threonine protein kinase antibody, Fas-interacting serine/threonine-protein kinase antibody, FIST antibody, FIST3 antibody, Hipk3 antibody, HIPK3_HUMAN antibody, homeodomain interacting protein kinase 3 antibody, Homeodomain-interacting protein kinase 3 antibody, Homolog of protein kinase YAK1 antibody, PKY antibody, RP24 297H17.5 antibody, YAK1 antibody
- UniProt
- Q9H422
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