SETD7 抗体 (AA 1-218)
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- 抗原 See all SETD7 抗体
- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
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抗原表位
- AA 1-218
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SETD7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Histone-lysine N-methyltransferase SETD7 protein (1-218AA)
- 亚型
- IgG
- Top Product
- Discover our top product SETD7 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
- 别名
- SETD7 (SETD7 产品)
- 别名
- KMT7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, set7 antibody, zgc:101860 antibody, zgc:92330 antibody, 1600028F23Rik antibody, H3K4MT antibody, Set7 antibody, Set7/9 antibody, mKIAA1717 antibody, SET domain containing lysine methyltransferase 7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SETD7 antibody, setd7 antibody, Setd7 antibody
- 背景
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Background: Histone methyltransferase that specifically monomethylates \\\'Lys-4\\\' of histone H3. H3 \\\'Lys-4\\\' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates \\\'Lys-189\\\' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates \\\'Lys-372\\\' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
Aliases: FLJ21193 antibody, H3 K4 HMTase antibody, H3-K4-HMTase SETD7 antibody, H4 lysine 4 specific antibody, Histone H3 K4 methyltransferase antibody, Histone H3 lysine 4 specific methyltransferase antibody, Histone H3-K4 methyltransferase SETD7 antibody, Histone H4 K4 methyltransferase antibody, Histone lysine N methyltransferase antibody, Histone lysine N methyltransferase H3 lysine 4 specific SET7 antibody, Histone-lysine N-methyltransferase SETD7 antibody, KIAA1717 antibody, KMT7 antibody, Lysine methyltransferase antibody, Lysine N-methyltransferase 7 antibody, OTTHUMP00000164543 antibody, OTTHUMP00000220049 antibody, SET 7 antibody, SET 7/9 antibody, SET 9 antibody, SET D7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SET domain containing protein 7 antibody, SET domain containing protein 8 antibody, SET domain-containing protein 7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, Setd7 antibody, SETD7_HUMAN antibody
- UniProt
- Q8WTS6
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