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SAP18 抗体 (AA 2-153)

SAP18 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7155341
发货至: 中国
  • 抗原 See all SAP18 抗体
    SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))
    抗原表位
    • 8
    • 7
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-153
    适用
    • 29
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 26
    • 3
    克隆类型
    • 28
    • 1
    多克隆
    标记
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    This SAP18 antibody is un-conjugated
    应用范围
    • 27
    • 17
    • 7
    • 6
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Histone deacetylase complex subunit SAP18 protein (2-153AA)
    亚型
    IgG
    Top Product
    Discover our top product SAP18 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))
    别名
    SAP18 (SAP18 产品)
    别名
    zgc:73118 antibody, C530046K05Rik antibody, D11Ertd539e antibody, EMegR4 antibody, Sinbp1 antibody, 2HOR0202 antibody, SAP18P antibody, Sin3A-associated protein antibody, Sin3-associated polypeptide 18 antibody, Sin3A associated protein 18 antibody, Sin3A associated protein 18kDa S homeolog antibody, sap18 antibody, Sap18 antibody, sap18.S antibody, SAP18 antibody
    背景

    Background: Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. The ASAP complex can inhibit mRNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes), specifically inhibits the formation of proapoptotic isoforms such as Bcl-X(S), the activity is different from the established EJC assembly and function.

    Aliases: 18 kDa Sin3-associated polypeptide antibody, 2HOR0202 antibody, Cell growth-inhibiting gene 38 protein antibody, Histone deacetylase complex subunit SAP18 antibody, SAP18 antibody, SAP18_HUMAN antibody, Sin3-associated polypeptide p18 antibody

    UniProt
    O00422
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