HDAC1 抗体 (AA 1-482)
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- 抗原 See all HDAC1 抗体
- HDAC1 (Histone Deacetylase 1 (HDAC1))
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抗原表位
- AA 1-482
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HDAC1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Histone deacetylase 1 protein (1-482AA)
- 亚型
- IgG
- Top Product
- Discover our top product HDAC1 Primary Antibody
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anti-Histone Deacetylase 1 (HDAC1) antibody
KO Validated HDAC1 适用: 人 WB, IF, IP, IHC (p), ICC, ChIP, IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal E22 unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Histone Deacetylase 1 (HDAC1) antibodyKO Validated HDAC1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 450-482) antibodyHDAC1 适用: 人 WB, ELISA, IHC, IF, FM, MA 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 207-412) antibodyHDAC1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (C-Term) antibodyVerified HDAC1 适用: 人, 小鼠 WB, ELISA, IF, ChIP 宿主: 山羊 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (Middle Region) antibodyHDAC1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (C-Term) antibodyHDAC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:100-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- HDAC1 (Histone Deacetylase 1 (HDAC1))
- 别名
- HDAC1 (HDAC1 产品)
- 背景
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Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium stimulation, HDAC1 is released from the complex and CREBBP is recruited, which facilitates transcriptional activation. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Deacetylates \\\'Lys-310\\\' in RELA and thereby inhibits the transcriptional activity of NF-kappa-B. Deacetylates NR1D2 and abrogates the effect of KAT5-mediated relieving of NR1D2 transcription repression activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Involved in CIART-mediated transcriptional repression of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex or CRY1 through histone deacetylation.
Aliases: DKFZp686H12203 antibody, GON 10 antibody, HD1 antibody, HDAC 1 antibody, HDAC1 antibody, HDAC1_HUMAN antibody, Histone deacetylase 1 antibody, Reduced potassium dependency yeast homolog like 1 antibody, RPD3 antibody, RPD3L1 antibody
- UniProt
- Q13547
- 途径
- Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
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