HMGB3 抗体 (AA 1-103)
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- 抗原 See all HMGB3 抗体
- HMGB3 (High Mobility Group Box 3 (HMGB3))
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抗原表位
- AA 1-103
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HMGB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human High mobility group protein B3 protein (1-103AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- HMGB3 (High Mobility Group Box 3 (HMGB3))
- 别名
- HMGB3 (HMGB3 产品)
- 别名
- HMG-2a antibody, HMG-4 antibody, HMG2A antibody, HMG4 antibody, Hmg2a antibody, Hmg4 antibody, RGD1564407 antibody, hmgb3 antibody, MGC54022 antibody, Xhmgb3 antibody, MGC88931 antibody, fa19b06 antibody, fj43d02 antibody, wu:fa19b06 antibody, wu:fj43d02 antibody, zgc:112073 antibody, HMGB3 antibody, NFD03 antibody, NFD3 antibody, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR antibody, high mobility group B3 antibody, HMG-1 antibody, HMG2a antibody, HMGB1 antibody, high mobility group box 3 antibody, high mobility group box 3b antibody, high mobility group box 3 S homeolog antibody, high mobility group protein antibody, high mobility group B3 antibody, High mobility group protein B3 antibody, HMGB3 antibody, Hmgb3 antibody, hmgb3 antibody, hmgb3b antibody, hmgb3.S antibody
- 背景
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Background: Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).
Aliases: chromosomal protein, Nonhistone, HMG4 antibody, High mobility group (nonhistone chromosomal) protein 4 antibody, High mobility group box 3 antibody, High mobility group protein 2a antibody, High mobility group protein 4 antibody, High mobility group protein B3 antibody, High mobility group protein HMG4 antibody, HMG 4 antibody, HMG-2a antibody, HMG-4 antibody, HMG2A antibody, HMGB 3 antibody, Hmgb3 antibody, HMGB3_HUMAN antibody, MGC90319 antibody, Non histone chromosomal protein antibody, Nonhistone chromosomal protein HMG4 antibody
- UniProt
- O15347
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